Seabuckthorn has multiple-use properties. This review explores the medicinal applications of Hippophae rhamnoides in healing ailments. The plant is being used in different parts of the world for its nutritional and medicinal properties. Sea buckthorn-based preparations have been extensively exploited in folklore treatment of slow digestion, stomach malfunctioning, cardiovascular problems, liver injury, tendon and ligament injuries, skin diseases and ulcers. In recent years, the medicinal and pharmacological activities of Seabuckthorn have been well investigated using limited clinical trials. Homeopathy is a well-respected modality to assist wellness. Traditional and modern medicinal experts have been applied this plant to treat various diseases. Seabuckthorn is an important plant because of its immense medicinal and therapeutic potential. However, several knowledge gaps identified in this paper would give impetus to new academic and R&D activities, especially for the development of Sea buckthorn-based herbal medicine and nutraceuticals. Its full application in dermatology may be attributed to the presence of a variety of flavonoids, vitamins, and unsaturated fatty acids. Great use of the plant in the traditional system for dermatological aspects, demands further comprehensive phytochemical work based on its actual use by the traditional population. Anti-inflammation is the most important applicable ingredient of this miracle berry.
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