Review Article
Medical
Yang Yang; Yuxue Jiao; Mohammad Reza Mohammadi
Abstract
Protein is an important component of life. Protein modification after translation enriches the diversity of protein, regulates the structure and function of the protein, and participates in more life processes. Recent studies have found that post-translational modifications of proteins can regulate the ...
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Protein is an important component of life. Protein modification after translation enriches the diversity of protein, regulates the structure and function of the protein, and participates in more life processes. Recent studies have found that post-translational modifications of proteins can regulate the occurrence and development of tumors. This article reviews the current status of tumor immunotherapy and the types and effects of post-translational modifications of proteins, hoping to improve new ideas for the types of therapies. . The human immune system should be able to eliminate cancer cells through an acquired immune response executed by T cells. However, clinical detection of cancer cells often results from the failure of immune surveillance. Therefore, relieving immune suppression and restoring antitumor immune response provides the possibility for tumor therapy.Tumor immunotherapy refers to exogenous intervention of the body's immune system, restart and maintain the "tumor-immune" cycle, restore and improve the anti-immune response of the group, strengthen the recognition and killing ability of tumor cells, so as to achieve the therapeutic effect of controlling or even clarifying the tumor specifically.
Review Article
Medical
Farhad Nalaini; Saleh Salehi Zahabi; Mohadese Abdoli; Elham Kazemi; Mahmood Mehrbakhsh; Salar Khaledian; Reza Fatahian
Abstract
In this review, we will discuss the neuroimaging findings of patients with COVID-19 from the outbreak (late December 2019) to the end of October 2021. PubMed, Scopus, Google Scholar, Science Direct, ProQuest, Web of Science and the World Health Organization database (January 01, 2020, to October 30, ...
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In this review, we will discuss the neuroimaging findings of patients with COVID-19 from the outbreak (late December 2019) to the end of October 2021. PubMed, Scopus, Google Scholar, Science Direct, ProQuest, Web of Science and the World Health Organization database (January 01, 2020, to October 30, 2021) were searched for related published articles. In each of the databases, the appendix search strategies were performed and the below keywords were used: COVID-19 ”OR“coronavirus disease 2019” AND “brain MRI” OR “brain magnetic resonance imaging” OR “brain CT” OR “neuroimaging”. In total, neuroimaging findings of 1550 patients, with ages from 1-96 years, were analyzed. Most brain neuroimaging findings include hyperintensity, Cerebral venous thrombosis, intraventricular and subarachnoid hemorrhage, infarction, leukoencephalopathy, acute ischemic strokes and posterior reversible encephalopathy syndrome (PRES) in adult patients and severe encephalopathy, stroke, infarction, CNS infection/demyelination, neuritis or polyradiculitis, venous thrombosis, Guillain-Barré syndrome, and longitudinally extensive myelitis, and myositis in pediatric patients. Our findings showed that the most important complication of the coronavirus is not just respiratory complications, because although transiently, COVID-19-related brain complications are seen in pediatrics as well as adults, and families should pay more attention to health care.
Review Article
Biochemistry
Ruqayah Ali Salman
Abstract
Breast cancer, the most frequent disease in women worldwide, represents a significant public health concern on a global scale. Breast cancer was the most frequent type of cancer among Iraqi women in 2018, accounting for the highest percentage of malignant tumors in women. Breast cancer is a set of physiological ...
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Breast cancer, the most frequent disease in women worldwide, represents a significant public health concern on a global scale. Breast cancer was the most frequent type of cancer among Iraqi women in 2018, accounting for the highest percentage of malignant tumors in women. Breast cancer is a set of physiological and molecular heterogeneous diseases that begin in the breast. Advanced breast cancer with distant organ metastases is considered incurable with current therapies. Aside from new treatment improvements, the next global challenge in breast cancer care is equal worldwide access to therapeutic advances. The incidence of breast cancer continues to rise in every part of the world. Despite advances in its identification and treatment, which have resulted in lower mortality rates, it appears vital to seek out new therapeutic approaches, predictive and prognostic indicators. The article provides a literature review of breast carcinoma, a condition that affects women worldwide. As a result, women should be aware of the disease's course, the importance of regular screenings for early detection of breast cancer, and the best treatment options.
