Cell, Organ and Tissue Culture
Neonatal Screening for Glucose-6-phosphate dehydrogenase Deficiency in Ardabil Province, Iran, 2018-2019

Afshin Fathi; Manouchehr Barak; Mahshid Damandan; Firouz Amani; Rouhallah Moradpour; Irada Khalilova; Mehdi Valizadeh

Volume 1, Issue 1 , March 2021, , Pages 1-6

https://doi.org/10.55705/cmbr.2021.138793.1000

Abstract
  Glucose-6-phosphate dehydrogenase (G6PD) is one of the most common genetic deficiencies that affect approximately 400 million people worldwide. This study aimed to identify neonates with G6PD deficiency in Ardabil province during 2017-2018. This cross-sectional study was conducted on all term and preterm ...  Read More

Neonatal Screening for Glucose-6-phosphate dehydrogenase Deficiency in Ardabil Province, Iran, 2018-2019


Phytochemistry and Biosynthesis
Nitric oxide signaling pathway in medicinal plants

Ali Salehi-Sardoei; Halimeh Khalili

Volume 2, Issue 1 , March 2022, , Pages 1-9

https://doi.org/10.55705/cmbr.2022.330292.1019

Abstract
  Nitrogen monoxide or nitric oxide is a biological active growth regulator that a wide range of studies have recently shown that it acts as a growth regulator (signaling molecule) in plants. As soon as Nitric Oxide (NO) known as a new biological agent in plants and animals, biological branches of sciences ...  Read More

Nitric oxide signaling pathway in medicinal plants


Medical
Comparative study on the efficacy of statin therapy in lowering cholesterol and assessing the risk of metabolic syndrome in patients under statins therapy

Kodipelly Ramana Raju; Afreen Sharifa; Paspula Soumya; Rumana Khanam; Koyala konda Banda Sanjay Bhargav

Volume 3, Issue 1 , March 2023, , Pages 1-8

https://doi.org/10.55705/cmbr.2022.361364.1064

Abstract
  The objective of the study is to compare and evaluate the efficacy of atorvastatin (group – A) versus rosuvastatin (group – B) on baseline parameters like lipid profile tests and to assess the risk of metabolic syndrome using a Mets calculator. A total of 100 patients were enclosed in the ...  Read More

Comparative study on the efficacy of statin therapy in lowering cholesterol and assessing the risk of metabolic syndrome in patients under statins therapy


Medical
Investigating outbreaks caused by foodborne diseases and determining common bacterial agents that cause them in Kurdistan province

Mohammad Mehdi Soltan Dallal; Zahra Rajabi; Mohammad Reza Mohammadi; Arezoo Bagheri Sadegi

Volume 4, Issue 1 , March 2024, , Pages 1-8

https://doi.org/10.55705/cmbr.2023.384570.1098

Abstract
  Foodborne diseases are a global problem that is spreading day by day. These diseases are one of the most common causes of death in children and the elderly. This study was conducted to investigate the prevalence of water and foodborne diseases in Kurdistan province for six months from April to September ...  Read More

Investigating outbreaks caused by foodborne diseases and determining common bacterial agents that cause them in Kurdistan province


DNA, RNA, protein components
Association between Human Endogenous Retrovirus K gene expression and breast cancer

Masoud Tourang; Le Fang; Yuan Zhong; Ram Chandra Suthar

Volume 1, Issue 1 , March 2021, , Pages 7-13

https://doi.org/10.55705/cmbr.2021.138810.1008

Abstract
  Breast cancer is one of the most common cancers known, and it is also a significant cause of death in women. If breast cancer is diagnosed in the early stages of the disease and treated appropriately, we can see an increase in life expectancy for more than 90% of patients. Research on molecular biomarkers ...  Read More

Association between Human Endogenous Retrovirus K gene expression and breast cancer


Medical
Screening for some virulent factors among bacterial isolates from surfaces of hospital fomites and hands of healthcare workers

Musa Yakubu Tula; Joel Filgona; Serah Erold Kyauta; Richard Elisha

Volume 3, Issue 1 , March 2023, , Pages 9-16

https://doi.org/10.55705/cmbr.2022.355120.1054

Abstract
  The ability of the bacterial isolate to cause debilitating effects on the host is intricate and is a function of many factors, particularly that of the host and the bacteria. Among the bacterial factors are the virulence mechanisms. As such this research was a cross-sectional study conducted between ...  Read More

Screening for some virulent factors among bacterial isolates from surfaces of hospital fomites and hands of healthcare workers


System Biology
In vitro assessment of the Larvicidal activity of Bacillus thuringiensis israelensis (Vectobac 12AS formulation) on Anopheles mosquito larvae

Ismail Muhammad; Muinat Abdullahi Muhammad; Rejoice Asher; Abdulmalik Bala Shuaibu

Volume 4, Issue 1 , March 2024, , Pages 9-16

https://doi.org/10.55705/cmbr.2023.391224.1115

Abstract
  This research aimed to evaluate the larvicidal activity of the lower doses of commercially synthetic Bacillus thuringiensis israelensis (Vectobac 12 Aqueous Solution (12AS)) against the fourth instar larva. One hundred and fifty blood-fed female anopheles mosquitoes were collected from different resting ...  Read More

In vitro assessment of the Larvicidal activity of Bacillus thuringiensis israelensis (Vectobac 12AS formulation) on Anopheles mosquito larvae


Nano-Biotechnology
The efficiency of metal, metal oxide, and metalloid nanoparticles against cancer cells and bacterial pathogens: different mechanisms of action

Mehran Alavi; Mahendra Rai; Fleming Martinez; Danial Kahrizi; Haroon Khan; Irwin Rose Alencar de Menezes; Henrique Douglas Melo Coutinho; José Galberto Martins Costa

Volume 2, Issue 1 , March 2022, , Pages 10-21

https://doi.org/10.55705/cmbr.2022.147090.1023

Abstract
  The applications of nanoparticles in various practical fields, owing to their unique properties compared with bulk materials, have been occupying the minds of scientists for several decades. In this regard, a combination of pharmacology and nanotechnology has contributed to producing newer effective ...  Read More

The efficiency of metal, metal oxide, and metalloid nanoparticles against cancer cells and bacterial pathogens: different mechanisms of action


Cell, Organ and Tissue Culture
Cytotoxic effect of diferuloylmethane, a derivative of turmeric on different human glioblastoma cell lines

Ismael Bilal; Sijia Xie; Muna S Elburki; Zahra Aziziaram; Sangar Muhammad Ahmed; Salah Tofik Jalal Balaky

Volume 1, Issue 1 , March 2021, , Pages 14-22

https://doi.org/10.55705/cmbr.2021.138815.1004

Abstract
  Glioblastoma is a fatal brain tumor, and the standard treatment for this cancer is the surgical removal of the tumor followed by chemotherapy with temozolomide and radiotherapy. Because chemotherapy has many side effects, the use of compounds extracted from natural herbs, due to fewer side effects, can ...  Read More

Cytotoxic effect of diferuloylmethane, a derivative of turmeric on different human glioblastoma cell lines


Medical
Support and control during childbirth and attachment after birth in mothers referring to comprehensive health centers in Bijar, 2019

Hateme Alavi; Farzaneh Zaheri; Roonak Shahoei

Volume 3, Issue 1 , March 2023, , Pages 17-28

https://doi.org/10.55705/cmbr.2022.355559.1055

Abstract
  Childbirth is one of the most important experiences in the life of mothers, which can bring tensions and worries due to physical and psychological changes. Therefore, the present study was conducted to determine the amount of support and control during childbirth and attachment after birth in mothers ...  Read More

Support and control during childbirth and attachment after birth in mothers referring to comprehensive health centers in Bijar, 2019


Bioinformatics
The progress and development trends on stress granules in the world and China during the past 35 years

Wenyuan Li; Yao Wang

Volume 4, Issue 1 , March 2024, , Pages 17-29

https://doi.org/10.55705/cmbr.2023.400513.1155

Abstract
  Stress granules (SGs) will be produced when the body is under external stimuli, and SGs play an important role in the pathogenesis of more and more diseases. The study on SGs has generally grown to a comprehensive subject in the past 35 years (from 1988 to 2022). The bibliometric analysis was used to ...  Read More

The progress and development trends on stress granules in the world and China during the past 35 years


Genetic engineering
Therapeutic potential of Seabuckthorn (Hippophae rhamnoides L.) in medical sciences

Hamid Ahani; Soroush Attaran

Volume 2, Issue 1 , March 2022, , Pages 22-32

https://doi.org/10.55705/cmbr.2022.330326.1020

Abstract
  Seabuckthorn has multiple-use properties. This review explores the medicinal applications of Hippophae rhamnoides in healing ailments. The plant is being used in different parts of the world for its nutritional and medicinal properties. Sea buckthorn-based preparations have been extensively exploited ...  Read More

Therapeutic potential of Seabuckthorn (Hippophae rhamnoides L.) in medical sciences


Gene Expression Studies
Protective effects of curcumin against naproxen-induced mitochondrial dysfunction in rat kidney tissue

Zahra Aziziaram; Ismael Bilal; Yuan Zhong; Azzadin Kamal Mahmod; Mohammad Reza Roshandel

Volume 1, Issue 1 , March 2021, , Pages 23-32

https://doi.org/10.55705/cmbr.2021.138879.1001

Abstract
  Naproxen is a common analgesic and antipyretic medication that is widely used around the world. This medicine at high doses leads to liver and kidney necrosis in humans and animals. The mechanism of kidney damage, unlike liver damage, is not well understood and is one of the most common causes of emergency ...  Read More

Protective effects of curcumin against naproxen-induced mitochondrial dysfunction in rat kidney tissue


Biochemistry
Study of thyroid hormones effect on biochemical parameters of liver function in Iraqi patients

Huda Kadhim Jaafer; Melike Bilgi Kamac; Abdulnasser Mohammed Al-Gebori

Volume 3, Issue 1 , March 2023, , Pages 29-34

https://doi.org/10.55705/cmbr.2022.365507.1072

Abstract
  This study was aimed to study the effect of thyroid hormones on some biochemical tests of liver function in Iraqi male patients and to study the relationship between them. A controlled study included 135 samples from patients and controls, group B, 45 patients with a liver disorder, and group C: 45 patients ...  Read More

Study of thyroid hormones effect on biochemical parameters of liver function in Iraqi patients


Medical
The effect of chickpeas metabolites on human diseases and the application of their valuable nutritional compounds suitable for human consumption

Mehdi Kakaei; Fazal Ur Rehman; Farzaneh Fazeli

Volume 4, Issue 1 , March 2024, , Pages 30-42

https://doi.org/10.55705/cmbr.2023.395591.1153

Abstract
  Legumes provide a major portion of protein and calories in the diet of many people around the world. Among different legumes, chickpeas have higher bioavailability and protein. Legumes are the second most important source of human food after the cereal family. Among them, chickpea with 15 to 25% of protein ...  Read More

The effect of chickpeas metabolites on human diseases and the application of their valuable nutritional compounds suitable for human consumption


Gene Expression Studies
Relevance of genetic polymorphisms of the human cytochrome P450 3A4 in rivaroxaban-treated patients

Muhammed Furkan Ercisli; Gao Lechun; Sarhang Hasan Azeez; Rebwar Muhammad Hamasalih; Siyan Song; Zahra Aziziaram

Volume 1, Issue 1 , March 2021, , Pages 33-41

https://doi.org/10.55705/cmbr.2021.138880.1003

Abstract
  Rivaroxaban is an anticoagulant drug that prevents forming of blood clots. In addition, it can be administered to prevent and treat thrombotic diseases such as atrial fibrillation, cardiac arrhythmia, heart valve disease, orthopedic surgery, and thrombophilia to reduce the risk of thrombosis. Various ...  Read More

Relevance of genetic polymorphisms of the human cytochrome P450 3A4 in rivaroxaban-treated patients


Cell structural and functions
Cellular structure and molecular functions of plants, animals, bacteria, and viruses

Hamid kheyrodin; Raheba Jami; Fazal Ur Rehman

Volume 2, Issue 1 , March 2022, , Pages 33-41

https://doi.org/10.55705/cmbr.2022.330941.1021

Abstract
  Plant cells are the basic unit of life in organisms of the kingdom Plantae. These organisms as eukaryotic cells have a true nucleus along with particular structures called organelles that perform various functions.  The plant cell wall can provide a structural framework to support plant ...  Read More

Cellular structure and molecular functions of plants, animals, bacteria, and viruses


Nano-Biotechnology
Antibacterial silver nanoparticles: effects on bacterial nucleic acids

Mehran Alavi; Michael R. Hamblin

Volume 3, Issue 1 , March 2023, , Pages 35-40

https://doi.org/10.55705/cmbr.2022.361677.1065

Abstract
  Various microorganisms are located on the human skin, mucous membrane and inside the human body. Many of these microorganisms are beneficial and few are even essential, however, some pathogens are known to cause infection and have the ability to attack and damage the host tissue. Treatment of infectious ...  Read More

Antibacterial silver nanoparticles: effects on bacterial nucleic acids


Medical
Available drug therapies on COVID-19 and its side effects: An overview

Namrata Malik; Umesh Pravin Dhuldhaj

Volume 3, Issue 1 , March 2023, , Pages 41-61

https://doi.org/10.55705/cmbr.2022.364739.1071

Abstract
  The sudden outbreak of coronavirus turned into a pandemic and resulted in huge socio-economic and human losses becoming a public health emergency. It took just 3-4 months to spread and encroach all over the world and not even a single country is left was unaffected by the coronavirus. WHO started clinical, ...  Read More

Available drug therapies on COVID-19 and its side effects: An overview


Cell, Organ and Tissue Culture
Insulin-producing cells from bone marrow stem cells versus injectable insulin for the treatment of rats with type I diabetes

Sarhang Hasan Azeez; Sarwar Nawzad Jafar; Zahra Aziziaram; Le Fang; Ahang Hasan Mawlood; Muhammed Furkan Ercisli

Volume 1, Issue 1 , March 2021, , Pages 42-51

https://doi.org/10.55705/cmbr.2021.138888.1006

Abstract
  Recently, stem cells have been considered renewable cell sources in the treatment of diabetes and the development of insulin-producing cells. In this regard, the current study aimed to compare Insulin-producing cells from bone marrow stem cells with injectable insulin in rats with type I diabetes. For ...  Read More

Insulin-producing cells from bone marrow stem cells versus injectable insulin for the treatment of rats with type I diabetes


Gene Expression Studies
Molecular analysis of bio-makers of Chloroquine resistance in Plasmodium falciparum isolate from gombe local government area, Gombe State, Nigeria

Ismail Muhammad; Pukuma Micah Sale; Muhammad Khadija Salisu; Tanko Mahmoud Muhammad; Bala Abubakar; Augustine Linda Maidala; Enock Nuwanyada

Volume 2, Issue 1 , March 2022, , Pages 42-55

https://doi.org/10.55705/cmbr.2022.335753.1033

Abstract
  Chloroquine was one of the most cheapest and effective chemotherapeutic drugs for Plasmodium falciparum-malaria, but for a long, the drug has been officially withdrawn in almost all malaria-endemic countries including Nigeria, due to the development of resistance by the parasite. Withdrawal of the drug ...  Read More

Molecular analysis of bio-makers of Chloroquine resistance in Plasmodium falciparum isolate from gombe local government area, Gombe State, Nigeria


Bioinformatics
Identification of some Echinophora platyloba miRNAs using computational methods and the effect of these miRNAs in the expression of TLN2 and ZNF521 genes in different human body organs

Sahand Sasani; Sajad Rashidi Monfared; Ali Reza Mirzaei

Volume 4, Issue 1 , March 2024, , Pages 43-53

https://doi.org/10.55705/cmbr.2023.386145.1100

Abstract
  MicroRNAs (miRNAs) are small (~22 nucleotides) non-coding endogenous RNA molecules that negatively regulate gene expression at the post-transcriptional level by degrading the target protein-coding mRNA genes or suppressing translation in plants, which consequently participate in a variety of biological ...  Read More

Identification of some Echinophora platyloba miRNAs using computational methods and the effect of these miRNAs in the expression of TLN2 and ZNF521 genes in different human body organs


Nano-Biotechnology
Antisense RNA, the modified CRISPR-Cas9, and metal/metal oxide nanoparticles to inactivate pathogenic bacteria

Mehran Alavi; Mahendra Rai

Volume 1, Issue 2 , June 2021, , Pages 52-59

https://doi.org/10.55705/cmbr.2021.142436.1014

Abstract
  Finding efficient therapeutic strategies to fight antibiotic-resistant bacteria is a complicated affair specifically in the therapy of chronic bacterial infections related to hospital-acquired infections. Recently, three major antibacterial systems based on antisense RNA, CRISPR-Cas9, and metal/metal ...  Read More

Antisense RNA, the modified CRISPR-Cas9, and metal/metal oxide nanoparticles to inactivate pathogenic bacteria


Biochemistry
Polycystic Ovary Syndrome: pathogenesis, management, and treatment with metals and organic compounds

Tamara Ahmed Abd Al-Kareem; Shaimaa Ahmad Hassan; Saifaldeen Muwafag Abdalhadi

Volume 4, Issue 1 , March 2024, , Pages 54-64

https://doi.org/10.55705/cmbr.2023.406103.1160

Abstract
  Polycystic ovary syndrome (PCOS) is a popular illness in women after puberty age. It’s described via overdone androgen production, and ovulation unrest while elevating metabolic syndrome. PCOS was usually diagnosed by Ultrasound or blood test to check the androgens and other hormone levels. There ...  Read More

Polycystic Ovary Syndrome: pathogenesis, management, and treatment with metals and organic compounds


Medical
Evaluation of active pulmonary tuberculosis among women with diabetes

Razieh Behzadmehr; Khadije Rezaie-Keikhaie

Volume 2, Issue 1 , March 2022, , Pages 56-63

https://doi.org/10.55705/cmbr.2022.336572.1036

Abstract
  Diabetes is one of the most common non-contagious diseases in the world. This disease is the fourth or fifth cause of death in most developed countries. The relationship between tuberculosis and diabetes had been introduced years ago and diabetes is considered a threatening factor in tuberculosis in ...  Read More

Evaluation of active pulmonary tuberculosis among women with diabetes