Cell, Organ and Tissue Culture
1. Neonatal Screening for Glucose-6-phosphate dehydrogenase Deficiency in Ardabil Province, Iran, 2018-2019

Afshin Fathi; Manouchehr Barak; Mahshid Damandan; Firouz Amani; Rouhallah Moradpour; Irada Khalilova; Mehdi Valizadeh

Volume 1, Issue 1 , June 2021, , Pages 1-6

http://dx.doi.org/10.55705/cmbr.2021.138793.1000

Abstract
  Glucose-6-phosphate dehydrogenase (G6PD) is one of the most common genetic deficiencies that affect approximately 400 million people worldwide. This study aimed to identify neonates with G6PD deficiency in Ardabil province during 2017-2018. This cross-sectional study was conducted on all term and preterm ...  Read More

Neonatal Screening for Glucose-6-phosphate dehydrogenase Deficiency in Ardabil Province, Iran, 2018-2019


Phytochemistry and Biosynthesis
2. Nitric oxide signaling pathway in medicinal plants

Ali Salehi-Sardoei; Halimeh Khalili

Volume 2, Issue 1 , March 2022, , Pages 1-9

http://dx.doi.org/10.55705/cmbr.2022.330292.1019

Abstract
  Nitrogen monoxide or nitric oxide is a biological active growth regulator that a wide range of studies have recently shown that it acts as a growth regulator (signaling molecule) in plants. As soon as Nitric Oxide (NO) known as a new biological agent in plants and animals, biological branches of sciences ...  Read More

Nitric oxide signaling pathway in medicinal plants


DNA, RNA, protein components
3. Association between Human Endogenous Retrovirus K gene expression and breast cancer

Masoud Tourang; Le Fang; Yuan Zhong; Ram Chandra Suthar

Volume 1, Issue 1 , June 2021, , Pages 7-13

http://dx.doi.org/10.55705/cmbr.2021.138810.1008

Abstract
  Breast cancer is one of the most common cancers known, and it is also a significant cause of death in women. If breast cancer is diagnosed in the early stages of the disease and treated appropriately, we can see an increase in life expectancy for more than 90% of patients. Research on molecular biomarkers ...  Read More

Association between Human Endogenous Retrovirus K gene expression and breast cancer


Nano-Biotechnology
4. The efficiency of metal, metal oxide, and metalloid nanoparticles against cancer cells and bacterial pathogens: different mechanisms of action

Mehran Alavi; Mahendra Rai; Fleming Martinez; Danial Kahrizi; Haroon Khan; Irwin Rose Alencar de Menezes; Henrique Douglas Melo Coutinho; José Galberto Martins Costa

Volume 2, Issue 1 , March 2022, , Pages 10-21

http://dx.doi.org/10.55705/cmbr.2022.147090.1023

Abstract
  The applications of nanoparticles in various practical fields, owing to their unique properties compared with bulk materials, have been occupying the minds of scientists for several decades. In this regard, a combination of pharmacology and nanotechnology has contributed to producing newer effective ...  Read More

The efficiency of metal, metal oxide, and metalloid nanoparticles against cancer cells and bacterial pathogens: different mechanisms of action


Cell, Organ and Tissue Culture
5. Cytotoxic effect of diferuloylmethane, a derivative of turmeric on different human glioblastoma cell lines

Ismael Bilal; Sijia Xie; Muna S Elburki; Zahra Aziziaram; Sangar Muhammad Ahmed; Salah Tofik Jalal Balaky

Volume 1, Issue 1 , June 2021, , Pages 14-22

http://dx.doi.org/10.55705/cmbr.2021.138815.1004

Abstract
  Glioblastoma is a fatal brain tumor, and the standard treatment for this cancer is the surgical removal of the tumor followed by chemotherapy with temozolomide and radiotherapy. Because chemotherapy has many side effects, the use of compounds extracted from natural herbs, due to fewer side effects, can ...  Read More

Cytotoxic effect of diferuloylmethane, a derivative of turmeric on different human glioblastoma cell lines


Genetic engineering
6. Therapeutic potential of Seabuckthorn (Hippophae rhamnoides L.) in medical sciences

Hamid Ahani; Soroush Attaran

Volume 2, Issue 1 , March 2022, , Pages 22-32

http://dx.doi.org/10.55705/cmbr.2022.330326.1020

Abstract
  Seabuckthorn has multiple-use properties. This review explores the medicinal applications of Hippophae rhamnoides in healing ailments. The plant is being used in different parts of the world for its nutritional and medicinal properties. Sea buckthorn-based preparations have been extensively exploited ...  Read More

Therapeutic potential of Seabuckthorn (Hippophae rhamnoides L.) in medical sciences


Gene Expression Studies
7. Protective effects of curcumin against naproxen-induced mitochondrial dysfunction in rat kidney tissue

Zahra Aziziaram; Ismael Bilal; Yuan Zhong; Azzadin Kamal Mahmod; Mohammad Reza Roshandel

Volume 1, Issue 1 , June 2021, , Pages 23-32

http://dx.doi.org/10.55705/cmbr.2021.138879.1001

Abstract
  Naproxen is a common analgesic and antipyretic medication that is widely used around the world. This medicine at high doses leads to liver and kidney necrosis in humans and animals. The mechanism of kidney damage, unlike liver damage, is not well understood and is one of the most common causes of emergency ...  Read More

Protective effects of curcumin against naproxen-induced mitochondrial dysfunction in rat kidney tissue


Gene Expression Studies
8. Relevance of genetic polymorphisms of the human cytochrome P450 3A4 in rivaroxaban-treated patients

Muhammed Furkan Ercisli; Gao Lechun; Sarhang Hasan Azeez; Rebwar Muhammad Hamasalih; Siyan Song; Zahra Aziziaram

Volume 1, Issue 1 , June 2021, , Pages 33-41

http://dx.doi.org/10.55705/cmbr.2021.138880.1003

Abstract
  Rivaroxaban is an anticoagulant drug that prevents forming of blood clots. In addition, it can be administered to prevent and treat thrombotic diseases such as atrial fibrillation, cardiac arrhythmia, heart valve disease, orthopedic surgery, and thrombophilia to reduce the risk of thrombosis. Various ...  Read More

Relevance of genetic polymorphisms of the human cytochrome P450 3A4 in rivaroxaban-treated patients


Cell structural and functions
9. Cellular structure and molecular functions of plants, animals, bacteria, and viruses

Hamid kheyrodin; Raheba Jami; Fazal Ur Rehman

Volume 2, Issue 1 , March 2022, , Pages 33-41

http://dx.doi.org/10.55705/cmbr.2022.330941.1021

Abstract
  Plant cells are the basic unit of life in organisms of the kingdom Plantae. These organisms as eukaryotic cells have a true nucleus along with particular structures called organelles that perform various functions.  The plant cell wall can provide a structural framework to support plant ...  Read More

Cellular structure and molecular functions of plants, animals, bacteria, and viruses


Cell, Organ and Tissue Culture
10. Insulin-producing cells from bone marrow stem cells versus injectable insulin for the treatment of rats with type I diabetes

Sarhang Hasan Azeez; Sarwar Nawzad Jafar; Zahra Aziziaram; Le Fang; Ahang Hasan Mawlood; Muhammed Furkan Ercisli

Volume 1, Issue 1 , June 2021, , Pages 42-51

http://dx.doi.org/10.55705/cmbr.2021.138888.1006

Abstract
  Recently, stem cells have been considered renewable cell sources in the treatment of diabetes and the development of insulin-producing cells. In this regard, the current study aimed to compare Insulin-producing cells from bone marrow stem cells with injectable insulin in rats with type I diabetes. For ...  Read More

Insulin-producing cells from bone marrow stem cells versus injectable insulin for the treatment of rats with type I diabetes


Gene Expression Studies
11. Molecular analysis of Bio-makers of Chloroquine resistance in Plasmodium falciparum Isolate from Gombe Local Government Area, Gombe State, Nigeria

Ismail Muhammad; Pukuma Micah Sale; Muhammad Khadija Salisu; Tanko Mahmoud Muhammad; Bala Abubakar; Augustine Linda Maidala; Enock Nuwanyada

Volume 2, Issue 1 , March 2022, , Pages 42-55

http://dx.doi.org/10.55705/cmbr.2022.335753.1033

Abstract
  Chloroquine was one of the most cheapest and effective chemotherapeutic drugs for Plasmodium falciparum-malaria, but for a long, the drug has been officially withdrawn in almost all malaria-endemic countries including Nigeria, due to the development of resistance by the parasite. Withdrawal of the drug ...  Read More

Molecular analysis of Bio-makers of Chloroquine resistance in Plasmodium falciparum Isolate from Gombe Local Government Area, Gombe State, Nigeria


Nano-Biotechnology
12. Antisense RNA, the modified CRISPR-Cas9, and metal/metal oxide nanoparticles to inactivate pathogenic bacteria

Mehran Alavi; Mahendra Rai

Volume 1, Issue 2 , December 2021, , Pages 52-59

http://dx.doi.org/10.55705/cmbr.2021.142436.1014

Abstract
  Finding efficient therapeutic strategies to fight antibiotic-resistant bacteria is a complicated affair specifically in the therapy of chronic bacterial infections related to hospital-acquired infections. Recently, three major antibacterial systems based on antisense RNA, CRISPR-Cas9, and metal/metal ...  Read More

Antisense RNA, the modified CRISPR-Cas9, and metal/metal oxide nanoparticles to inactivate pathogenic bacteria


Medical
13. Evaluation of Active Pulmonary Tuberculosis Among Women With Diabetes

Razieh Behzadmehr; Khadije Rezaie-Keikhaie

Volume 2, Issue 1 , March 2022, , Pages 56-63

http://dx.doi.org/10.55705/cmbr.2022.336572.1036

Abstract
  Diabetes is one of the most common non-contagious diseases in the world. This disease is the fourth or fifth cause of death in most developed countries. The relationship between tuberculosis and diabetes had been introduced years ago and diabetes is considered a threatening factor in tuberculosis in ...  Read More

Evaluation of Active Pulmonary Tuberculosis Among Women With Diabetes


DNA, RNA, protein components
14. Evaluation of antibiotic resistance and prevalence of multi-antibiotic resistant genes among Acinetobacter baumannii strains isolated from patients admitted to al-yarmouk hospital

Zahraa Khudhair Abbas-Al-Khafaji; Qassim hassan Aubais-aljelehawy

Volume 1, Issue 2 , December 2021, , Pages 60-68

http://dx.doi.org/10.55705/cmbr.2021.142761.1015

Abstract
  Emerging antibiotic resistance in microorganisms particularly multidrug-resistant strains among bacteria are increasing because of misusing antibiotics as well as evolution of antibiotic resistance mechanisms. In this regard, Acinetobacter baumannii is one of the six most common multidrug-resistant microorganisms ...  Read More

Evaluation of antibiotic resistance and prevalence of multi-antibiotic resistant genes among Acinetobacter baumannii strains isolated from patients admitted to al-yarmouk hospital


Bioinformatics
15. Bioinformatics analysis and pharmacological effect of Stevia rebaudiana in the prevention of type-2 diabetes

Ali Reza Mirzaei; Vida Shakoory-Moghadam

Volume 2, Issue 2 , June 2022, , Pages 64-73

http://dx.doi.org/10.55705/cmbr.2022.336232.1035

Abstract
  Different groups of enzymes and regulatory elements are involved in the synthesis of Ribodioside A, which is one of the most important sweetening compounds in stevia. The UGT family (UDP-glycosyltransferase) is a group of regulatory genes that are very effective in converting steviol glycoside to Ribodioside ...  Read More

Bioinformatics analysis and pharmacological effect of Stevia rebaudiana in the prevention of type-2 diabetes


DNA, RNA, protein components
16. Overview of typing techniques as molecular epidemiology tools for bacterial characterization

Nasim Almasian-Tehrani; Masoud Alebouyeh; Shahnaz Armin; Neda Soleimani; Leila Azimi; Roozbeh Shaker-Darabad

Volume 1, Issue 2 , December 2021, , Pages 69-77

http://dx.doi.org/10.55705/cmbr.2021.143413.1016

Abstract
  The main purpose of microbial typing is to evaluate the relationships between microbial isolates. Microbial typing can use for identifying the source of infection by detecting a clonal link between the strains. Moreover, it can analyze outbreaks, antimicrobial-resistant strains, and evaluate the effectiveness ...  Read More

Overview of typing techniques as molecular epidemiology tools for bacterial characterization


Medical
17. Effect of unripe fruit extract of Momordica charantia on total cholesterol, total triglyceride and blood lipoproteins in the blood of rats with hyperlipidemia

Mehdi Doosti-Moghaddam; Hamid Reza Miri; Arezo Ghahghaei; Mohammad Reza Haginegd; Hadi Saboori

Volume 2, Issue 2 , June 2022, , Pages 74-86

http://dx.doi.org/10.55705/cmbr.2022.338806.1038

Abstract
  Hyperlipidemia is a major risk factor for the development of cardiovascular disease. In this study, the effects of an unripe fruit extract of Momordica charantia on total cholesterol, total triglyceride and lipoproteins in the blood of mice with hyperlipidemia were investigated. In this study, 28 adult ...  Read More

Effect of unripe fruit extract of Momordica charantia on total cholesterol, total triglyceride and blood lipoproteins in the blood of rats with hyperlipidemia


Gene Expression Studies
18. Evaluation of virulence factors among Staphylococcus aureus strains isolated from patients with urinary tract infection in Al-Najaf Al-Ashraf teaching hospital

Qassim hassan Aubais aljelehawy; Layth Hussein Hadi Alshaibah; Zahraa Khudhair Abbas Al- Khafaji

Volume 1, Issue 2 , December 2021, , Pages 78-87

http://dx.doi.org/10.55705/cmbr.2021.144995.1017

Abstract
  Staphylococcus aureus contains numerous surface proteins called microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) that mediate binding to host tissues and initiate colonization leading to infection. Virulence genes such as enzymes, toxins, adhesin proteins, cell surface proteins ...  Read More

Evaluation of virulence factors among Staphylococcus aureus strains isolated from patients with urinary tract infection in Al-Najaf Al-Ashraf teaching hospital


Nano-Biotechnology
19. Surface modification of SiO2 nanoparticles for bacterial decontaminations of blood products

Mehran Alavi; Michael R. Hamblin; M. R. Mozafari; Irwin Rose Alencar de Menezes; Henrique Douglas Melo Coutinho

Volume 2, Issue 2 , June 2022, , Pages 87-97

http://dx.doi.org/10.55705/cmbr.2022.338888.1039

Abstract
  Bacterial infections can be caused by contamination of labile blood products with specific bacteria, such as Staphylococcus aureus and Staphylococcus epidermidis. Hospital equipment, bio-protective equipment, delivery systems, and medical devices can be easily contaminated by microorganisms. Multidrug-resistant ...  Read More

Surface modification of SiO2 nanoparticles for bacterial decontaminations of blood products


Nuclear function
20. Clinical challenges of stress cardiomyopathy during coronavirus 2019 epidemic

Ebrahim Rahbar-Karbasdehi; Fatemeh Rahbar-Karbasdehi

Volume 1, Issue 2 , December 2021, , Pages 88-90

http://dx.doi.org/10.55705/cmbr.2021.145790.1018

Abstract
  A type of viral pneumonia that broke out in Wuhan, China in December 2019, and new strains of it are spreading rapidly around the world, is called coronavirus disease 2019 (COVID-19). The incidence of cardiovascular complications has increased both in the general population and in patients diagnosed ...  Read More

Clinical challenges of stress cardiomyopathy during coronavirus 2019 epidemic


Cell, Organ and Tissue Culture
21. Blood Sugar Changes in Patients with Acute Drug Poisoning

Khadije Saravani; Mahdi Afshari; Alireza Aminisefat; Omid Bameri

Volume 1, Issue 2 , December 2021, , Pages 91-97

http://dx.doi.org/10.55705/cmbr.2021.146061.1022

Abstract
  Changes in blood sugar in poisoning can be one of the most important determinants of the outcome of patients with poisoning. Since poisoning is one of the most common and increasing causes of death worldwide and one of the most critical medical emergencies, this study aimed to investigate changes in ...  Read More

Blood Sugar Changes in Patients with Acute Drug Poisoning


Medical
22. When Successive Viral Mutations Prevent Definitive Treatment of COVID-19

Mohammad Reza Mohammadi; Hoda Sabati

Volume 2, Issue 2 , June 2022, , Pages 98-108

http://dx.doi.org/10.55705/cmbr.2022.339012.1040

Abstract
  NCP (new coronavirus pneumonia) was discovered in Wuhan towards the end of 2019 and quickly spread throughout the city. The infection was identified as a novel coronavirus, and the World Health Organization (WHO) called it coronavirus disease-19 (COVID-19). Most people with this infection can experience ...  Read More

When Successive Viral Mutations Prevent Definitive Treatment of COVID-19


Application of medicinal plants in medicine
23. Antibacterial and antifungal activities of medicinal plant species and endophytes

Shirin Ahmadi

Volume 2, Issue 2 , June 2022, , Pages 109-115

http://dx.doi.org/10.55705/cmbr.2022.340532.1042

Abstract
  Systemic bacterial and fungal infections in recent years due to the increasing number of debilitating diseases immune system such as AIDS, blood malignancies, overdose, corticosteroid drugs, and broad-spectrum antibiotics has been raised. There is a prevalence of acute and subsequent candida infections ...  Read More

Antibacterial and antifungal activities of medicinal plant species and endophytes