Medical
Prevalence of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli associated with outbreaks of food-borne gastroenteritis in Tehran

Mohammad Mehdi Soltan Dallal; Zahra Rajabi; Moslem Papizadeh; Samaneh Amiri; Abbas Rahimi Foroushani; Ahmad Naser; Seyedeh Zohre Mirbagheri; Hossein Masoumi-Asl; Parisa Torabi; Mehrnaz Mirza Babaei

Articles in Press, Accepted Manuscript, Available Online from 11 August 2023

https://doi.org/10.55705/cmbr.2023.396644.1154

Abstract
  The prevalence of antibiotic resistance has been demonstrated in various food-borne pathogens. Beta-lactam antibiotics are among the first-line antimicrobials that are normally administered in case of gastrointestinal infections. However, Escherichia coli (E. coli) and some other members of Enterobacteriaceae ...  Read More

Medical
Evaluation of the prevalent genotypes of human papillomavirus in the population of women in Golestan province in the northeastern of Iran

Kamran Vosoo; Abdolazim Sarli; Yousef Yousefi; Sareh Khavand; Farasat Veisi

Articles in Press, Accepted Manuscript, Available Online from 21 November 2023

https://doi.org/10.55705/cmbr.2023.417181.1180

Abstract
  Human papillomavirus(HPV) is a viral infection that usually causes growths on mucous membranes or skin (warts). It has been confirmed that there are more than 100 types of human papilloma-virus (HPV). Some types of HPV infections cause warts, and some of them may cause different types of cancer. One ...  Read More

Medical
Effect of vitamin D supplementation on glycemic control in type 1 diabetes mellitus

Mohammed Shaker Al-Awady; Besma Mohammed Ali

Articles in Press, Accepted Manuscript, Available Online from 21 January 2024

https://doi.org/10.55705/cmbr.2024.436594.1218

Abstract
  Diabetes mellitus is a group of metabolic diseases with high prevalence, mortality and morbidity characterized by prolonged high blood glucose concentrations resulting from defects in insulin secretion, insulin action, or both. This study aimed to assess the role of vitamin D supplementation in glycemic ...  Read More

Medical
Antibiotic resistance pattern of Methicillin-resistant Staphylococcus aureus isolated from hospitalized patients

Fatemeh Shamakhte; Elaha Tajbakhsh; Hassan Momtaz

Articles in Press, Accepted Manuscript, Available Online from 16 March 2024

https://doi.org/10.55705/cmbr.2024.442150.1221

Abstract
  Methicillin-resistant S. aureus (MRSA) strains circulating among populations and crossing borders constitute a major problem for health control and require a fast and simple genotypic approach. The objective of this study was to determine the prevalence, molecular types and drug resistance pattern of ...  Read More

Medical
Evaluation of antibacterial activity of ozonated oil and ozonated water against Neisseria gonorrhoeae and Neisseria meningitidis by broth microdilution method

Zahra Yekanipour; Hamed Afkhami; Parya Amini; Mohammad Reza Mohammadi; Zahra Rafiei Atani; Kianoosh Dadashzadeh

Volume 4, Issue 3 , September 2024, , Pages 129-137

https://doi.org/10.55705/cmbr.2023.408352.1161

Abstract
  The necessity of using ozonated oil and water for treating infections such as gonorrhea and meningitis which their treatment by common antibiotics is sometimes difficult and it is becoming more apparent every day.  In this study, the antibacterial effect of ozonated oil and water against Neisseria ...  Read More

Evaluation of antibacterial activity of ozonated oil and ozonated water against Neisseria gonorrhoeae and Neisseria meningitidis by broth microdilution method


Medical
A study to assess the associated risk of developing cardiovascular diseases in chronic kidney disease

Bujagouni Swapna; Kaneez Fathima; Hifsa Muwayyad; Madeeha Khanam; Syeda Salma; Surabhi Harsha; Numair Gayas

Volume 4, Issue 3 , September 2024, , Pages 150-158

https://doi.org/10.55705/cmbr.2023.420751.1184

Abstract
  Chronic kidney disease (CKD) is on the rise around the world and is strongly linked with the incidence of cardiovascular disease (CVD). This six-month observational study was conducted in the nephrology division of a 300-bed, multi-specialty tertiary care teaching hospital. A total of 90 prescriptions ...  Read More

A study to assess the associated risk of developing cardiovascular diseases in chronic kidney disease


Medical
An outlook study on the combination of pharmacotherapy and physical rehabilitation for clinically significant acute ischemic stroke patients

Koteswari Poluri; Bujagouni Swapna; Vatte Jyothsna; Kaneez Fathima; Omamah Afreen; Shaheroz Jabeen; Sumera Sultana

Volume 4, Issue 3 , September 2024, , Pages 168-176

https://doi.org/10.55705/cmbr.2023.421498.1185

Abstract
  The occurrence of an ischemic stroke arises from the unfortunate circumstance in which a blood vessel becomes impeded or obstructed, resulting from the presence of a clot, atherosclerosis, or the narrowing of arteries. The neurology department of a 300-bed, multi-specialty tertiary teaching hospital ...  Read More

An outlook study on the combination of pharmacotherapy and physical rehabilitation for clinically significant acute ischemic stroke patients


Medical
The role of microglia in depression

Lester Raymundo Dominguez Huarcaya; María Fernanda Dominguez Ríos; Mohammad Reza Mohammadi; Zahra Rahimi

Volume 4, Issue 2 , June 2024, , Pages 74-87

https://doi.org/10.55705/cmbr.2023.409233.1162

Abstract
  At least in some individuals, the development of major depressive disorder (MDD) appears to be significantly influenced by neuroinflammation. Microglia, which are situated within the brain, represent a type of immune cell that exhibits the capability to transform into a reactive state in response to ...  Read More

The role of microglia in depression


Medical
Structural carcinoma overall process: a systematic review

Ali Reza Arabestanino; Seyed Sina Naghibi Irvani; Arman Ai; Bita Dinarvand

Volume 4, Issue 2 , June 2024, , Pages 88-99

https://doi.org/10.55705/cmbr.2023.410370.1164

Abstract
  Abnormalities of several oncogenes and tumor suppressor genes have been identified in carcinomas during the last decade and of pathological warfare and physiological traits, and multiple genetic changes have been demonstrated in individual carcinomas. We conducted a systematic review of studies enrolling ...  Read More

Structural carcinoma overall process: a systematic review


Medical
Evaluation of the level of liver enzymes and its relationship with ferritin and the frequency of blood transfusion in patients with thalassemia

Khadije Saravani; Pouya Ostadrahimi; Atena Jahanifard

Volume 4, Issue 2 , June 2024, , Pages 100-110

https://doi.org/10.55705/cmbr.2023.410242.1163

Abstract
  Thalassemia major is the most common hemolytic anemia in Iran and the world that causes an increase in complications in patients, one of the most important of which is liver complications. Therefore, this study aimed to evaluate the level of liver enzymes and their relationship with ferritin and the ...  Read More

Evaluation of the level of liver enzymes and its relationship with ferritin and the frequency of blood transfusion in patients with thalassemia


Medical
Frequency of aac (6 ́)-le-aph (2 ́ ́) gene and resistance to Aminoglycoside antibiotics in Staphylococcus aureus isolates

Sara Amini; Amir Hossein Omidi; Hamed Afkhami; Hoda Sabati; Amin Mohsenzadeh; Atyieh Soleymani; Mohammad Ali Zonobian; Negin Ghanbarnejad; Mohammad Reza Mohammadi

Volume 4, Issue 2 , June 2024, , Pages 120-128

https://doi.org/10.55705/cmbr.2023.411361.1166

Abstract
  Staphylococcus aureus is one of the most common infectious bacterial species and one of the agents of community-acquired infections (CAIs) and hospital-acquired infections (HAIs). Aminoglycosides are potent antibactericidal agents often used together with Beta Lactams or Glycopeptides, especially in ...  Read More

Frequency of aac (6 ́)-le-aph (2 ́ ́) gene and resistance to Aminoglycoside antibiotics in Staphylococcus aureus isolates


Medical
Investigating outbreaks caused by foodborne diseases and determining common bacterial agents that cause them in Kurdistan province

Mohammad Mehdi Soltan Dallal; Zahra Rajabi; Mohammad Reza Mohammadi; Arezoo Bagheri Sadegi

Volume 4, Issue 1 , March 2024, , Pages 1-8

https://doi.org/10.55705/cmbr.2023.384570.1098

Abstract
  Foodborne diseases are a global problem that is spreading day by day. These diseases are one of the most common causes of death in children and the elderly. This study was conducted to investigate the prevalence of water and foodborne diseases in Kurdistan province for six months from April to September ...  Read More

Investigating outbreaks caused by foodborne diseases and determining common bacterial agents that cause them in Kurdistan province


Medical
The effect of chickpeas metabolites on human diseases and the application of their valuable nutritional compounds suitable for human consumption

Mehdi Kakaei; Fazal Ur Rehman; Farzaneh Fazeli

Volume 4, Issue 1 , March 2024, , Pages 30-42

https://doi.org/10.55705/cmbr.2023.395591.1153

Abstract
  Legumes provide a major portion of protein and calories in the diet of many people around the world. Among different legumes, chickpeas have higher bioavailability and protein. Legumes are the second most important source of human food after the cereal family. Among them, chickpea with 15 to 25% of protein ...  Read More

The effect of chickpeas metabolites on human diseases and the application of their valuable nutritional compounds suitable for human consumption


Medical
Post-translational modifications of proteins in tumor immunotherapy and their potential as immunotherapeutic targets

Yang Yang; Yuxue Jiao; Mohammad Reza Mohammadi

Volume 3, Issue 4 , December 2023, , Pages 172-184

https://doi.org/10.55705/cmbr.2023.378480.1091

Abstract
  Protein is an important component of life. Protein modification after translation enriches the diversity of protein, regulates the structure and function of a protein, and participates in more life processes. Recent studies have found that post-translational modifications of proteins can regulate the ...  Read More

Post-translational modifications of proteins in tumor immunotherapy and their potential as immunotherapeutic targets


Medical
Pregnancy-induced hypertension: risk factors and current treatment strategies

CH Satish Kumar; Sayoni Roy; Talari Aishwarya; Chilkuri Shashank Setty; Omamah Afreen; Ammapally Maheshwari; Hafsa Ansari

Volume 3, Issue 4 , December 2023, , Pages 197-204

https://doi.org/10.55705/cmbr.2023.387076.1111

Abstract
  Hypertensive disorders during pregnancy are a major public health concern in both developed and developing countries. Early detection and treatment of maternal health issues reduce the severity of these issues. This study set out to identify possible risk factors of these conditions and evaluate ...  Read More

Pregnancy-induced hypertension: risk factors and current treatment strategies


Medical
COVID-19 and Brain complications in adult and pediatric patients: A review on neuroimaging findings

Farhad Nalaini; Saleh Salehi Zahabi; Mohadese Abdoli; Elham Kazemi; Mahmood Mehrbakhsh; Salar Khaledian; Reza Fatahian

Volume 3, Issue 4 , December 2023, , Pages 212-221

https://doi.org/10.55705/cmbr.2023.380339.1094

Abstract
  In this review, we will discuss the neuroimaging findings of patients with COVID-19 from the outbreak (late December 2019) to the end of October 2021. PubMed, Scopus, Google Scholar, Science Direct, ProQuest, Web of Science and the World Health Organization database (January 01, 2020, to October 30, ...  Read More

COVID-19 and Brain complications in adult and pediatric patients: A review on neuroimaging findings


Medical
The comparison of umbilical cord artery pH in newborns with and without thick meconium stained amniotic fluid

Nooshin Amjadi; Maryam Talayeh; Mohadeseh Momeni; Nasrin Mansouri

Volume 3, Issue 4 , December 2023, , Pages 222-226

https://doi.org/10.55705/cmbr.2023.388391.1112

Abstract
  Meconium-stained amniotic fluid (MSAF) affects 15-20% of term pregnancies. Recent studies have shown that MSAF has adverse effects on neonatal outcomes. There is no scientific consensus on the incidence of fetal distress in MSAF neonates, and most cesarean sections due to MSAF are unnecessary. The present ...  Read More

The comparison of umbilical cord artery pH in newborns with and without thick meconium stained amniotic fluid


Medical
Research progress on therapeutic effect and mechanism of hydrocortisone on sepsis

Yicen Long; Xiaoqiang Du; Zhi Ouyang; Jian Zhong; Ye Zeng

Volume 3, Issue 3 , September 2023, , Pages 122-129

https://doi.org/10.55705/cmbr.2023.377524.1090

Abstract
  Sepsis has remained a high mortality rate worldwide. Endothelial cell dysfunction is closely associated with the development of sepsis. Hydrocortisone has potent immunological and antitoxic effects, and thus it is frequently used in the treatment of septic shock. However, it can also cause respiratory ...  Read More

Research progress on therapeutic effect and mechanism of hydrocortisone on sepsis


Medical
New analytical method development and validation for estimation of molnupiravir in bulk and tablet dosage form by RP-HPLC method

Gandu Sravanthi; Kumara Swamy Gandla; Lalitha Repudi

Volume 3, Issue 3 , September 2023, , Pages 130-136

https://doi.org/10.55705/cmbr.2023.375093.1087

Abstract
  A new simple, selective, rapid, precise reversed-phase high-performance liquid chromatography method has been developed and validated for the estimation of Molnupiravir in bulk and its pharmaceutical dosage form. The separation was made using Symmetry ODS C18 (4.6×150mm, 5µm) column. The ...  Read More

New analytical method development and validation for estimation of molnupiravir in bulk and tablet dosage form by RP-HPLC method


Medical
A study on uterine fibroids effective treatment and associated risks factors in the tertiary care teaching hospital

CH Satish Kumar; Keshamoni Anusha; Rajoli Priyanka; Medipally Gowthami; Kaneez Fathima; Syed Sadiya Riaz; Bujagouni Swapna

Volume 3, Issue 3 , September 2023, , Pages 137-144

https://doi.org/10.55705/cmbr.2023.384489.1096

Abstract
  More than 75% of women have uterine fibroids (leiomyomas), which may have major morbid effects. By far, they are the main reason for a hysterectomy. Smooth muscle cells and fibroblasts make up the complicated cellular assemblage known as fibroids. They generally develop from somatic mutations, most often ...  Read More

A study on uterine fibroids effective treatment and associated risks factors in the tertiary care teaching hospital


Medical
Chromoblastomycosis successfully treated with the combination of itraconazole and 5-flucytosine

Reginaldo Gon De Lima-Neto; Mohammad Reza Mohammadi

Volume 3, Issue 3 , September 2023, , Pages 145-151

https://doi.org/10.55705/cmbr.2023.378135.1092

Abstract
  Chromoblastomycosis (CBM) is a fungal disease, distributed in tropical and subtropical regions, affecting mainly rural workers. It is characterized by chronic skin lesions that may vary from nodular, tumorous, verrucous or plaque type. Associated constitutional symptoms are rarely found. The histological ...  Read More

Chromoblastomycosis successfully treated with the combination of itraconazole and 5-flucytosine


Medical
Performance and accuracy of SD Bioline malaria Ag P.f (05fk50) in relation to microscopy as the gold standard technique for malaria diagnosis

Ismail Muhammad; Pukuma Mikah Sale; Tanko Mahmoud Muhammad; Ali Rufai; Augustine Linda Midala; Bala Abubakar

Volume 3, Issue 3 , September 2023, , Pages 152-161

https://doi.org/10.55705/cmbr.2023.376615.1089

Abstract
  Successful malaria diagnosis is the mainstay of successful treatment, prevention and eradication of malaria infection. Apart from the gold standard technique (Microscopy), numerous diagnostic techniques perform a similar function to microscopy and in most cases tend to have varying sensitivity and specificity, ...  Read More

Performance and accuracy of SD Bioline malaria Ag P.f (05fk50) in relation to microscopy as the gold standard technique for malaria diagnosis


Medical
Investigation of GJB2 and SLC26A4 genes related to pendred syndrome genetic deafness patients

Haider Majid Haider Al-Zaidi; Fatemehsadat Mousavinasab; Nika Radseresht; Ali Reza Mirzaei; Yasaman Moradi; Mohammad Mahmoudifar

Volume 3, Issue 3 , September 2023, , Pages 163-171

https://doi.org/10.55705/cmbr.2023.379262.1093

Abstract
  Deafness can occur due to damage to the ear, especially the inner ear. In other cases, the cause is a heterogeneous genetic abnormality and is caused by the changes that occur in the genes involved in the hearing process. Mutations in GJB2 and SLC26A4 genes are one of the most important causes of deafness ...  Read More

Investigation of GJB2 and SLC26A4 genes related to pendred syndrome genetic deafness patients


Medical
MicroRNAs; their therapeutic and biomarker properties

Shahnam Azizi Dargahlou; Marcello Iriti; Mahin Pouresmaeil; Lucky Poh Wah Goh

Volume 3, Issue 2 , June 2023, , Pages 73-88

https://doi.org/10.55705/cmbr.2022.365396.1085

Abstract
  MicroRNAs (miRNAs) are, small (roughly 19–25 nucleotides in length), conserved, non-coding, single-stranded, and functional RNA molecules with the properties of gene expression regulation through mRNA degradation, translation repression, mRNA deadenylation as well as gene silencing via histone ...  Read More

MicroRNAs; their therapeutic and biomarker properties


Medical
Comprehensive analysis of microRNA (miRNA) in cancer cells

Naghmana Kanwal; Othman Rashid Al Samarrai; Haider Majid Haider Al-Zaidi; Ali Reza Mirzaei; Mohammad Javad Heidari

Volume 3, Issue 2 , June 2023, , Pages 89-97

https://doi.org/10.55705/cmbr.2022.364591.1070

Abstract
  MicroRNAs (miRNA) are a group of small non-coding RNAs that regulate gene expression at the RNA level. MicroRNAs have positive regulatory effects on protein translation processes and often induce their performance by binding to the 3'-UTR mRNA region. Also, microRNAs are involved in various cellular ...  Read More

Comprehensive analysis of microRNA (miRNA) in cancer cells