Medical
Comprehensive analysis of microRNA (miRNA) in cancer cells

Ali Reza Mirzaei; Othman Rashid Al Samarrai; Mohammad Javad Heidari

Articles in Press, Accepted Manuscript, Available Online from 20 November 2022

https://doi.org/10.55705/cmbr.2022.364591.1070

Abstract
  MicroRNAs (miRNA) are a group of small non-coding RNAs that regulate gene expression at the RNA level. MicroRNAs have positive regulatory effects on protein translation processes and often induce their performance by binding to the 3'-UTR mRNA region. Also, microRNAs are involved in various cellular ...  Read More

Medical
MicroRNAs and their therapeutic and biomarker properties

Shahnam Azizi Dargahlou; Marcello Iriti; Mahin Pouresmaeil

Articles in Press, Accepted Manuscript, Available Online from 02 December 2022

https://doi.org/10.55705/cmbr.2022.365396.1085

Abstract
  MicroRNAs (miRNAs) are, small (roughly 19–25 nucleotides in length), conserved, non-coding, single-stranded, and functional RNA molecules with the properties of gene expression regulation through mRNA degradation, translation repression, mRNA deadenylation as well as gene silencing via histone ...  Read More

Medical
Comparative study on the efficacy of statin therapy in lowering cholesterol and assessing the risk of metabolic syndrome in patients under statins therapy

Kodipelly Ramana Raju; Afreen Sharifa; Paspula Soumya; Rumana Khanam; Koyala konda Banda Sanjay Bhargav

Volume 3, Issue 1 , March 2023, , Pages 1-8

https://doi.org/10.55705/cmbr.2022.361364.1064

Abstract
  The objective of the study is to compare and evaluate the efficacy of atorvastatin (group – A) versus rosuvastatin (group – B) on baseline parameters like lipid profile tests and to assess the risk of metabolic syndrome using a Mets calculator. A total of 100 patients were enclosed in the ...  Read More

Comparative study on the efficacy of statin therapy in lowering cholesterol and assessing the risk of metabolic syndrome in patients under statins therapy


Medical
Screening for some virulent factors among bacterial isolates from surfaces of hospital fomites and hands of healthcare workers

Musa Yakubu Tula; Joel Filgona; Serah Erold Kyauta; Richard Elisha

Volume 3, Issue 1 , March 2023, , Pages 9-16

https://doi.org/10.55705/cmbr.2022.355120.1054

Abstract
  The ability of the bacterial isolate to cause debilitating effects on the host is intricate and is a function of many factors, particularly that of the host and the bacteria. Among the bacterial factors are the virulence mechanisms. As such this research was a cross-sectional study conducted between ...  Read More

Screening for some virulent factors among bacterial isolates from surfaces of hospital fomites and hands of healthcare workers


Medical
Support and control during childbirth and attachment after birth in mothers referring to comprehensive health centers in Bijar, 2019

Hateme Alavi; Farzaneh Zaheri; Roonak Shahoei

Volume 3, Issue 1 , March 2023, , Pages 17-28

https://doi.org/10.55705/cmbr.2022.355559.1055

Abstract
  Childbirth is one of the most important experiences in the life of mothers, which can bring tensions and worries due to physical and psychological changes. Therefore, the present study was conducted to determine the amount of support and control during childbirth and attachment after birth in mothers ...  Read More

Support and control during childbirth and attachment after birth in mothers referring to comprehensive health centers in Bijar, 2019


Medical
Available drug therapies on COVID-19 and its side effects: An overview

Namrata Malik; Umesh Pravin Dhuldhaj

Volume 3, Issue 1 , March 2023, , Pages 41-61

https://doi.org/10.55705/cmbr.2022.364739.1071

Abstract
  The sudden outbreak of coronavirus turned into a pandemic and resulted in huge socio-economic and human losses becoming a public health emergency. It took just 3-4 months to spread and encroach all over the world and not even a single country is left was unaffected by the coronavirus. WHO started clinical, ...  Read More

Available drug therapies on COVID-19 and its side effects: An overview


Medical
Preterm birth: causes and complications observed in tertiary care hospitals

Poluri Koteswari; Pilly Aishwarya Lakshmi; Mohammed Yaseen; Sameera sultana; Amena Tabassum; Paspula Soumya; Aasimah Kawkab

Volume 2, Issue 4 , December 2022, , Pages 202-2012

https://doi.org/10.55705/cmbr.2022.362506.1068

Abstract
  The main aim of the study was to identify factors associated with preterm birth. The study was conducted for a period of 6 months from September 2019 to February 2020 in 1607 women at SVS Medical College and Hospital, and Sushrutha Hospital, Mahabubnagar and it eventually selected 80 pregnant women for ...  Read More

Preterm birth: causes and complications observed in tertiary care hospitals


Medical
A Systematic review on the status of diarrheagenic Escherichia coli (DEC) pathotypes in Nigeria; the year 2000 – 2022

Musa Yakubu Tula; Joel Filgona; Musa Sale Pukuma

Volume 2, Issue 4 , December 2022, , Pages 213-229

https://doi.org/10.55705/cmbr.2022.357758.1061

Abstract
  This systematic review appraised the current status of DEC in Nigeria from the year 2000 to August 2022 with regards to their prevalence, pathotypes distribution, and dominance within the 6 geopolitical zones. Three research databases (AJOL, PubMed, and Google Scholar) were explored for articles of interest. ...  Read More

A Systematic review on the status of diarrheagenic Escherichia coli (DEC) pathotypes in Nigeria; the year 2000 – 2022


Medical
The capacity of stem cells in treatment of diabetes

Farzaneh Fazeli; Masumeh Ahanjan

Volume 2, Issue 4 , December 2022, , Pages 230-244

https://doi.org/10.55705/cmbr.2022.357066.1060

Abstract
  Diabetes, a chronic metabolic disease, is recognized as the most frequent disorder in the endocrine system with hyperglycemia dealing with either insulin resistance or insufficiency or both. This disease is usually associated with numerous acute and chronic complications. Also, the treatment of diabetes ...  Read More

The capacity of stem cells in treatment of diabetes


Medical
Investigating the structure and function of Long Non-Coding RNA (LncRNA) and its role in cancer

Hasan Kamel Alsaedy; Ali Reza Mirzaei; Redha Alwan Hasan Alhashimi

Volume 2, Issue 4 , December 2022, , Pages 245-253

https://doi.org/10.55705/cmbr.2022.360799.1062

Abstract
  Cancer is one of the most complex and common diseases affected by many factors. In recent years, many studies have been conducted on the genetic characteristics of cancer, among which we can mention lncRNA Long Non-Coding RNAs, which effectively eliminate cancer tumors. LncRNAs are non-coding protein ...  Read More

Investigating the structure and function of Long Non-Coding RNA (LncRNA) and its role in cancer


Medical
Performance analysis of polymerase chain reaction in relation to rapid diagnostic test (RDT) kit (SD bio line malaria ag p.f (05fk50)) for malaria diagnosis

Ismail Muhammad; Pukuma Micah Sale; Tanko Mahmoud Mohammed; Saleh Zaliha Miyim; Asiya Muhammad Usman

Volume 2, Issue 4 , December 2022, , Pages 254-264

https://doi.org/10.55705/cmbr.2022.361911.1066

Abstract
  Malaria control and its elimination heavenly depend on successful and reliable diagnosis using recommended diagnostic techniques. These available techniques often have certain peculiarities and mode applications, thus making them have different levels of performance and accuracy. Therefore the aim of ...  Read More

Performance analysis of polymerase chain reaction in relation to rapid diagnostic test (RDT) kit (SD bio line malaria ag p.f (05fk50)) for malaria diagnosis


Medical
A prospective observational study to assess the cardiac risk factors and treatment patterns in established heart diseases

Palle Rishitha Reddy; Golla Poojitha; Sandaram Kavitha; Syeda Lubna Samreen; Ayman Naseer; Poluri Koteswari; Paspula Soumya

Volume 2, Issue 4 , December 2022, , Pages 265-275

https://doi.org/10.55705/cmbr.2022.362447.1067

Abstract
  The study aimed to assess established and non-established risk factors and drug therapy problems in the cardiology department and perform a Prospective Observational Study. The study was conducted for a period of 6 months from September 2019 to February 2020 in 200 patients with established heart diseases ...  Read More

A prospective observational study to assess the cardiac risk factors and treatment patterns in established heart diseases


Medical
Current trends and new methods of detection of SARS-CoV-2 infection

Mohammad Reza Mohammadi; Amir Hossein Omidi; Hoda Sabati

Volume 2, Issue 3 , September 2022, , Pages 138-150

https://doi.org/10.55705/cmbr.2022.345025.1047

Abstract
  SARS-CoV- 2 is the causative agent of the global pandemic, also known as Covid-19. This virus belongs to a group of coronaviruses and has affected more than ten million people across the globe, causing nearly half a million deaths worldwide. The pandemic has spread worldwide, originating in the Wuhan ...  Read More

Current trends and new methods of detection of SARS-CoV-2 infection


Medical
GC-MS Analysis of the Active Compound in Ethanol Extracts of White Pepper (Piper nigrum L.) and Pharmacological Effects

I Nyoman Arsana; Ni Ketut Ayu Juliasih; A A Ayu Sauca Sunia Widyantari; Ni Luh Suriani; Agus Manto

Volume 2, Issue 3 , September 2022, , Pages 151-161

https://doi.org/10.55705/cmbr.2022.351720.1051

Abstract
  Pepper (Piper nigrum L.) has been utilized since antiquity and is considered the king of spices due to its wide use. This study aims to analyze the active compounds of white pepper through GC-MS and their pharmacological effects. Pepper seeds were extracted using 96% ethanol as solvent by the maceration ...  Read More

GC-MS Analysis of the Active Compound in Ethanol Extracts of White Pepper (Piper nigrum L.) and Pharmacological Effects


Medical
Effect of unripe fruit extract of Momordica charantia on total cholesterol, total triglyceride and blood lipoproteins in the blood of rats with hyperlipidemia

Mehdi Doosti-Moghaddam; Hamid Reza Miri; Arezou Ghahghaei; Mohammad Reza Hajinezhad; Hadi Saboori

Volume 2, Issue 2 , June 2022, , Pages 74-86

https://doi.org/10.55705/cmbr.2022.338806.1038

Abstract
  Hyperlipidemia is a major risk factor for the development of cardiovascular disease. In this study, the effects of an unripe fruit extract of Momordica charantia on total cholesterol, total triglyceride and lipoproteins in the blood of mice with hyperlipidemia were investigated. In this study, 28 adult ...  Read More

Effect of unripe fruit extract of Momordica charantia on total cholesterol, total triglyceride and blood lipoproteins in the blood of rats with hyperlipidemia


Medical
When Successive Viral Mutations Prevent Definitive Treatment of COVID-19

Mohammad Reza Mohammadi; Hoda Sabati

Volume 2, Issue 2 , June 2022, , Pages 98-108

https://doi.org/10.55705/cmbr.2022.339012.1040

Abstract
  NCP (new coronavirus pneumonia) was discovered in Wuhan towards the end of 2019 and quickly spread throughout the city. The infection was identified as a novel coronavirus, and the World Health Organization (WHO) called it coronavirus disease-19 (COVID-19). Most people with this infection can experience ...  Read More

When Successive Viral Mutations Prevent Definitive Treatment of COVID-19


Medical
Genetic resistance to human malaria

Ismail Muhammad; Bala Abubakar; Tanko Mahmoud Muhammad

Volume 2, Issue 2 , June 2022, , Pages 116-128

https://doi.org/10.55705/cmbr.2022.342533.1043

Abstract
  Human beings are sometime expose to the same to predisposing factors of a given infectious disease, but the outcome in terms of disease manifestation differs greatly. This variation is mainly attributed to the genetic makeup of such individuals; this is because human genetic has long been associated ...  Read More

Genetic resistance to human malaria


Medical
Evaluation of Active Pulmonary Tuberculosis Among Women With Diabetes

Razieh Behzadmehr; Khadije Rezaie-Keikhaie

Volume 2, Issue 1 , March 2022, , Pages 56-63

https://doi.org/10.55705/cmbr.2022.336572.1036

Abstract
  Diabetes is one of the most common non-contagious diseases in the world. This disease is the fourth or fifth cause of death in most developed countries. The relationship between tuberculosis and diabetes had been introduced years ago and diabetes is considered a threatening factor in tuberculosis in ...  Read More

Evaluation of Active Pulmonary Tuberculosis Among Women With Diabetes


Medical
An introduction on cerebrovascular aneurysms during pregnancy

Khadije Saravani; Zahra Mirsarzai; Monireh Sekhavati

Volume 1, Issue 3 , December 2021, , Pages 98-104

https://doi.org/10.55705/cmbr.2021.356664.1057

Abstract
  A cerebral aneurysm is an abnormal bulge in the cerebral artery that spreads where the blood vessel wall has weakened. Cerebral aneurysms may allow blood to leak into the subcutaneous space around the brain and cause damage to brain cells. Brain aneurysms can also be ruptured and can lead to serious ...  Read More

An introduction on cerebrovascular aneurysms during pregnancy


Medical
Prevalence of hepatitis B in HIV-positive patients in Zabol

Leli Rezaie-Kahkhaie; Khadije Saravani; Khadije Rezaie-Keikhaie; Seyed Esmaeil Azimi-Khatibani; Abdul Hafiz Daman-Sooz; Mehdi Afshari; Atefeh kamali

Volume 1, Issue 3 , December 2021, , Pages 105-112

https://doi.org/10.55705/cmbr.2021.356667.1058

Abstract
  Today, due to the increase in life expectancy in HIV-infected patients, the incidence of related diseases such as hepatitis B and C due to similarity in transmission routes has become a major concern of the health community. Therefore, this study was performed to determine the prevalence of hepatitis ...  Read More

Prevalence of hepatitis B in HIV-positive patients in Zabol


Medical
The relationship between IL23R 1142G / A (Arg381Gln) and GM-CSF 3928 C / T (Ile117Thr) gene polymorphism in Iranian patients with tuberculosis disease

Kolsoum Rezaie-Kahkhaie; Khadije Rezaie-Keikhaie; Leli Rezaie-Kahkhaie; Khadije Saravani; Atefeh kamali

Volume 1, Issue 3 , December 2021, , Pages 113-121

https://doi.org/10.55705/cmbr.2021.356674.1059

Abstract
  The DNA polymorphisms found in clinical strains of Mycobacterium tuberculosis drive altered physiology, virulence, and pathogenesis in them. This study aimed to investigate the association between IL23R 1142 G/A (Arg381Gln) and GM-CSF 3928 C/T (Ile117Thr) gene polymorphisms with the incidence rate of ...  Read More

The relationship between IL23R 1142G / A (Arg381Gln) and GM-CSF 3928 C / T (Ile117Thr) gene polymorphism in Iranian patients with tuberculosis disease


Medical
Clinical analysis of diagnosing a case with tuberculous peritonitis from Afghanistan

Mohammad Reza Mohammadi; Mahram Ali Mehran; Amir Hossein Omidi; Mohammad Hadi Hassani

Volume 1, Issue 3 , December 2021, , Pages 122-128

https://doi.org/10.55705/cmbr.2021.354911.1053

Abstract
  Tuberculosis is a contagious infectious disease. This disease is called tuberculosis and is abbreviated as TB. Tuberculosis is one of the most important infectious diseases of this century, which can involve all the organs of the body, but the lungs are most affected by tuberculosis. The occurrence of ...  Read More

Clinical analysis of diagnosing a case with tuberculous peritonitis from Afghanistan


Medical
A retrospective observational study to assess the cirrhosis risk in alcoholic patients

Paspula Soumya; Thurupu Sai Priya; Hameed Alla Qureshi; Alisha Firdous

Volume 1, Issue 3 , December 2021, , Pages 129-137

https://doi.org/10.55705/cmbr.2021.361362.1063

Abstract
  Cirrhosis is a late-stage liver disease in which/ advanced stage of scaring and conditions, such as hepatitis and chronic alcoholism. This disease is a condition in which your liver is scarred and permanently damaged. Scar tissue replaces healthy liver tissue and prevents your liver from working normally. ...  Read More

A retrospective observational study to assess the cirrhosis risk in alcoholic patients