Gene Expression Studies
Prevalence of RDB, RSa, Hinc and Xmn polymorphisms and HBBS11D haplotypes in patients with thalassemia minor

Seyyedeh Shabnam Irankhah; Saied Hoseini-Asl; Mehdi Valizadeh; Firouz Amani

Volume 2, Issue 3 , September 2022, , Pages 162-172

https://doi.org/10.55705/cmbr.2022.348456.1049

Abstract
  Background: Beta-thalassemia is one of the most common genetic diseases with autosomal recessive inherited patterns in the world and is one of the most common diseases in Iran that exists in all age and sex groups. Determining gene mutations in this disease can be effective in controlling and treating ...  Read More

Prevalence of RDB, RSa, Hinc and Xmn polymorphisms and HBBS11D haplotypes in patients with thalassemia minor


Gene Expression Studies
Molecular analysis of Bio-makers of Chloroquine resistance in Plasmodium falciparum Isolate from Gombe Local Government Area, Gombe State, Nigeria

Ismail Muhammad; Pukuma Micah Sale; Muhammad Khadija Salisu; Tanko Mahmoud Muhammad; Bala Abubakar; Augustine Linda Maidala; Enock Nuwanyada

Volume 2, Issue 1 , March 2022, , Pages 42-55

https://doi.org/10.55705/cmbr.2022.335753.1033

Abstract
  Chloroquine was one of the most cheapest and effective chemotherapeutic drugs for Plasmodium falciparum-malaria, but for a long, the drug has been officially withdrawn in almost all malaria-endemic countries including Nigeria, due to the development of resistance by the parasite. Withdrawal of the drug ...  Read More

Molecular analysis of Bio-makers of Chloroquine resistance in Plasmodium falciparum Isolate from Gombe Local Government Area, Gombe State, Nigeria


Gene Expression Studies
Evaluation of virulence factors among Staphylococcus aureus strains isolated from patients with urinary tract infection in Al-Najaf Al-Ashraf teaching hospital

Qassim hassan Aubais aljelehawy; Layth Hussein Hadi Alshaibah; Zahraa Khudhair Abbas Al- Khafaji

Volume 1, Issue 2 , August 2021, , Pages 78-87

https://doi.org/10.55705/cmbr.2021.144995.1017

Abstract
  Staphylococcus aureus contains numerous surface proteins called microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) that mediate binding to host tissues and initiate colonization leading to infection. Virulence genes such as enzymes, toxins, adhesin proteins, cell surface proteins ...  Read More

Evaluation of virulence factors among Staphylococcus aureus strains isolated from patients with urinary tract infection in Al-Najaf Al-Ashraf teaching hospital


Gene Expression Studies
Protective effects of curcumin against naproxen-induced mitochondrial dysfunction in rat kidney tissue

Zahra Aziziaram; Ismael Bilal; Yuan Zhong; Azzadin Kamal Mahmod; Mohammad Reza Roshandel

Volume 1, Issue 1 , April 2021, , Pages 23-32

https://doi.org/10.55705/cmbr.2021.138879.1001

Abstract
  Naproxen is a common analgesic and antipyretic medication that is widely used around the world. This medicine at high doses leads to liver and kidney necrosis in humans and animals. The mechanism of kidney damage, unlike liver damage, is not well understood and is one of the most common causes of emergency ...  Read More

Protective effects of curcumin against naproxen-induced mitochondrial dysfunction in rat kidney tissue


Gene Expression Studies
Relevance of genetic polymorphisms of the human cytochrome P450 3A4 in rivaroxaban-treated patients

Muhammed Furkan Ercisli; Gao Lechun; Sarhang Hasan Azeez; Rebwar Muhammad Hamasalih; Siyan Song; Zahra Aziziaram

Volume 1, Issue 1 , April 2021, , Pages 33-41

https://doi.org/10.55705/cmbr.2021.138880.1003

Abstract
  Rivaroxaban is an anticoagulant drug that prevents forming of blood clots. In addition, it can be administered to prevent and treat thrombotic diseases such as atrial fibrillation, cardiac arrhythmia, heart valve disease, orthopedic surgery, and thrombophilia to reduce the risk of thrombosis. Various ...  Read More

Relevance of genetic polymorphisms of the human cytochrome P450 3A4 in rivaroxaban-treated patients